Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis.
Tian R, Abarientos A, Hong J, Hashemi SH, Yan R, Drager N, Leng K, Nalls MA, Singleton AB, Xu K, Faghri F, Kampmann M
Nat Neurosci. 2021 May 24. pii: 10.1038/s41593-021-00862-0. doi: 10.1038/s41593-021-00862-0.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 158091 | pRT043-CLYBL-DDdcas9-VPH | Inducible expression of dCas9-VPH from the CLYBL locus for CRISPR activation |