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Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis.

Moro L, Simoneschi D, Kurz E, Arbini AA, Jang S, Guaragnella N, Giannattasio S, Wang W, Chen YA, Pires G, Dang A, Hernandez E, Kapur P, Mishra A, Tsirigos A, Miller G, Hsieh JT, Pagano M
Nat Cell Biol. 2020 Sep;22(9):1130-1142. doi: 10.1038/s41556-020-0560-6. Epub 2020 Aug 24. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
171848pcDNA3-FLAG_FBXL7pcDNA3-FLAG_FBXL7
171849pcDNA3-FLAG_FBXL7 (R310H)pcDNA3-FLAG_FBXL7 (R310H)
171850pEGFP-N1_c-SRCpEGFP-N1_c-SRC

Antibodies from Article