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Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor.

Antonia AL, Barnes AB, Martin AT, Wang L, Ko DC
PLoS Negl Trop Dis. 2021 Oct 28;15(10):e0009224. doi: 10.1371/journal.pntd.0009224. eCollection 2021 Oct. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
171642Lmajor_gp63_28_0570_WTExpression of wildtype L. major glcyoprotein-63 from chromosome 28 in mammalian cells
171643Lmajor_gp63_31_2000_WTExpression of wildtype L. major glcyoprotein-63 from chromosome 31 in mammalian cells
171644Lmajor_gp63_10_0460_D463NExpression of L. major glcyoprotein-63 (D463N) with substrate binding site mutation from chromosome 10 in mammalian cells
171645Lmajor_gp63_10_0460_P460G_D463N_S465AExpression of L. major glcyoprotein-63 (P460G_D463N_S465A) with substrate binding site mutations from chromosome 10 in mammalian cells

Antibodies from Article