ATP13A2 deficiency disrupts lysosomal polyamine export.
van Veen S, Martin S, Van den Haute C, Benoy V, Lyons J, Vanhoutte R, Kahler JP, Decuypere JP, Gelders G, Lambie E, Zielich J, Swinnen JV, Annaert W, Agostinis P, Ghesquiere B, Verhelst S, Baekelandt V, Eggermont J, Vangheluwe P
Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
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Plasmids from Article
ID | Plasmid | Purpose |
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171377 | pYeDP60-hATP13A2-WT | A modified pYEDP60 plasmid containing a yeast codon-optimized version of human ATP13A2 variant 2, followed by a thrombin cleavage site and a C-terminal BAD tag. DOI: 10.21769/BioProtoc.3888 |
171378 | pYeDP60-hATP13A2-E343A | A modified pYEDP60 plasmid containing a yeast codon-optimized version of human ATP13A2 variant 2 E343A mutant, followed by a thrombin cleavage site and a C-term BAD tag. DOI: 10.21769/BioProtoc.3888 |
171485 | pLenti HsATP13A2 WT | transfer plasmid for lentiviral vector production expressing Hs ATP13A2 WT |
171771 | miR3 Mm ATP13A2 | transfer plasmid for lentiviral vector production with miR for Mm ATP13A2 |
171820 | pLenti HsATP13A2 D508N | transfer plasmid for lentiviral vector production expressing Hs ATP13A2 D508N |
171821 | pLenti HsATP13A2 D962N | transfer plasmid for lentiviral vector production expressing Hs ATP13A2 D962N |
171822 | miR5 Mm ATP13A2 | transfer plasmid for lentiviral vector production with miR for Mm ATP13A2 |