Dominant-negative Galpha subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease.
Marivin A, Leyme A, Parag-Sharma K, DiGiacomo V, Cheung AY, Nguyen LT, Dominguez I, Garcia-Marcos M
Sci Signal. 2016 Apr 12;9(423):ra37. doi: 10.1126/scisignal.aad2429.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 171375 | pcDNA3.1(-)-Gαi3-YFP (Citrine variant, b/c loop insert) | For the mammalian expression of rat Gαi3 internally tagged with YFP |