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Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.

Ogden TEH, Yang JC, Schimpl M, Easton LE, Underwood E, Rawlins PB, McCauley MM, Langelier MF, Pascal JM, Embrey KJ, Neuhaus D
Nucleic Acids Res. 2021 Feb 26;49(4):2266-2288. doi: 10.1093/nar/gkab020. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
169815PARP1 FLExpresses codon optimised full length His tagged PARP1 in bacterial cells

Antibodies from Article