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Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB
Cell. 2021 Mar 12. pii: S0092-8674(21)00298-1. doi: 10.1016/j.cell.2021.03.013. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
169459pTwist-SARS-CoV-2 Δ18 B.1.1.7Encodes SARS-CoV-2 B.1.1.7 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169460pTwist-SARS-CoV-2 Δ18 B.1.1.298Encodes SARS-CoV-2 B.1.1.298 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169461pTwist-SARS-CoV-2 Δ18 B.1.429Encodes SARS-CoV-2 B.1.429 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169462pTwist-SARS-CoV-2 Δ18 B.1.351v1Encodes SARS-CoV-2 B.1.351v1 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169463pTwist-SARS-CoV-2 Δ18 B.1.351v2Encodes SARS-CoV-2 B.1.351v2 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169464pTwist-SARS-CoV-2 Δ18 B.1.351v3Encodes SARS-CoV-2 B.1.351v3 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169465pTwist-SARS-CoV Δ18Encodes SARS-CoV Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169466pTwist-SARS-CoV-2 Δ18 B.1.351v1/wtRBDEncodes SARS-CoV-2 B.1.351v1/wtRBD Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169467pTwist-SARS-CoV-2 Δ18 B.1.351v2/wtRBDEncodes SARS-CoV-2 B.1.351v2/wtRBD Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169468pTwist-SARS-CoV-2 Δ18 B.1.351v3/wtRBDEncodes SARS-CoV-2 B.1.351v3/wtRBD Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
169469pTwist-SARS-CoV-2 Δ18 K417N+E484K+N501YEncodes SARS-CoV-2 K417N+E484K+N501Y Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
173476pTwist-SARS-CoV-2 Δ18 P.1Encodes SARS-CoV-2 P.1 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production
173477pTwist-SARS-CoV-2 Δ18 P.2/B.1.1.248Encodes SARS-CoV-2 P.2/B.1.1.248 Spike Protein lacking 18 C-terminal amino acids for pseudovirus production

Antibodies from Article