High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer.
Pierce SE, Granja JM, Greenleaf WJ
Nat Commun. 2021 May 20;12(1):2969. doi: 10.1038/s41467-021-23213-w.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169235 | pSP618 | Spear-ATAC lentiviral backbone - includes a mU6-sgRNA cassette with flanking Nextera sequencing adapters |