EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.
Gautheron J, Morisseau C, Chung WK, Zammouri J, Auclair M, Baujat G, Capel E, Moulin C, Wang Y, Yang J, Hammock BD, Cerame B, Phan F, Feve B, Vigouroux C, Andreelli F, Jeru I
Elife. 2021 Aug 3;10. pii: 68445. doi: 10.7554/eLife.68445.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169169 | pCMV6-Entry-EPHX1c.337T>C-Flag | Expresses EPHX1 c.337T>C in mammalian cells |
| 169170 | pCMV6-Entry-EPHX1c.416A>G-Flag | Expresses EPHX1 c.416A>G in mammalian cells |
| 169171 | pCMV6-Entry-EPHX1c.997A>C-Flag | Expresses EPHX1 c.997A>C in mammalian cells |
| 169172 | pCMV6-Entry-EPHX1c.1212G>C-Flag | Expresses EPHX1 c.1212G>C in mammalian cells |
| 169173 | pCMV6-Entry-EPHX1c.1288G>C-Flag | Expresses EPHX1 c.1288G>C in mammalian cells |