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Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals.

Parker JL, Deme JC, Wu Z, Kuteyi G, Huo J, Owens RJ, Biggin PC, Lea SM, Newstead S
Sci Adv. 2021 Aug 25;7(35). pii: 7/35/eabh3355. doi: 10.1126/sciadv.abh3355. Print 2021 Aug. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
167988pLexm-gfp-Pept2expresses rat PepT2 with a c terminal cleavable GFP-His tag.
167989pBXPHM3-NB-D6expression of a nanobody against rat PepT2 as a n terminal MBP fusion

Antibodies from Article