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HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells.

Nguyen DTT, Lu Y, Chu KL, Yang X, Park SM, Choo ZN, Chin CR, Prieto C, Schurer A, Barin E, Savino AM, Gourkanti S, Patel P, Vu LP, Leslie CS, Kharas MG
Nat Commun. 2020 Apr 24;11(1):2026. doi: 10.1038/s41467-020-15814-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
166967MSI2-ADAExpress the fusion protein of human MSI2 and the hyperactive catalytic domain of Drosophila ADAR
166968MSI2-DCDExpress the fusion protein of human MSI2 and the catalytic dead domain of Drosophila ADAR
166969HyperADAR controlExpress the Hyperactive catalytic domain of Drosophila ADAR and linker at the 5' end of this domain, in the MSCV-IRES-GFP

Antibodies from Article