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TopBP1 assembles nuclear condensates to switch on ATR signaling.

Frattini C, Promonet A, Alghoul E, Vidal-Eychenie S, Lamarque M, Blanchard MP, Urbach S, Basbous J, Constantinou A
Mol Cell. 2021 Jan 16. pii: S1097-2765(20)30991-6. doi: 10.1016/j.molcel.2020.12.049. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
166504pCDNA5_FRT_TO_TurboID-mCherry-Cry2Expression of your protein of interest fused with TurboID and mcherry-CRY2 for optogenetic activation, Flp-In T-Rex system. Search for client proteins within light-induced biomolecular condensates.

Antibodies from Article