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Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization.

Deffieu MS, Clement CMH, Dorobantu CM, Partiot E, Bare Y, Faklaris O, Riviere B, Ayala-Nunez NV, Baumert TF, Ronde P, Mely Y, Lucansky V, Gaudin R
Hepatology. 2022 Apr 7. doi: 10.1002/hep.32514. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
166133pLenti KO CLDN1 2xgRNA - spCas9 iRFP670 puroThis plasmid allows efficient KO of the cldn1 gene, while expressing the far red fluorescent protein iRFP670 and puromycin resistance
166134pLenti KO Luc Firefly 2xgRNA - spCas9 iRFP670 puroThis plasmid allows efficient KO of the firefly luciferase gene, while expressing the far red fluorescent protein iRFP670 and puromycin resistance

Antibodies from Article