Cancer associated talin point mutations disorganise cell adhesion and migration.
Azizi L, Cowell AR, Mykuliak VV, Goult BT, Turkki P, Hytonen VP
Sci Rep. 2021 Jan 11;11(1):347. doi: 10.1038/s41598-020-77911-4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 166112 | pEGFP_WT-talin1 (1-2541) | For expression of full-length wild-type mouse talin-1 in mammalian cells. Contains C-terminal EGFP tag. |
| 166113 | pEGFP_P229L-talin1 (1-2541) | expresses talin-1-P229L in mammalian cells |
| 166114 | pEGFP_I392N-talin1 (1-2541) | expresses talin-1-I392N in mammalian cells |
| 166115 | pEGFP_V577D-talin1 (1-2541) | expresses talin-1-V577D in mammalian cells |
| 166116 | pEGFP_A893E-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation A893E in mammalian cells. Contains C-terminal EGFP tag. |
| 166117 | pEGFP_R1368W-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation R1368W in mammalian cells. Contains C-terminal EGFP tag. |
| 166118 | pEGFP_Y1389C-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation Y1389C in mammalian cells. Contains C-terminal EGFP tag. |
| 166119 | pEGFP_L1539P-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation L1539P in mammalian cells. Contains C-terminal EGFP tag. |
| 166120 | pEGFP_S1750F-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation S1750F in mammalian cells. Contains C-terminal EGFP tag. |
| 166121 | pEGFP_E1770Q-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation E1770Q in mammalian cells. Contains C-terminal EGFP tag. |
| 166122 | pEGFP_D2086V-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation D2086V in mammalian cells. Contains C-terminal EGFP tag. |
| 166123 | pEGFP_L2509P-talin1 (1-2541) | For expression of full-length mouse talin-1 carrying mutation L2509P in mammalian cells. Contains C-terminal EGFP tag. |
| 166124 | pEGFP_∆DD-talin1 (1-2493) | For expression of mouse talin-1 (residues 1-2493) containing C-terminal deletion of dimerization domain (∆DD) in mammalian cells. Contains C-terminal EGFP tag. |
| 166125 | pEGFP_∆R13–DD-talin1 (1-2299) | For expression of mouse talin-1 (residues 1-2299) with C-terminal deletion of dimerization domain and R13 (∆R13-DD) in mammalian cells. Contains C-terminal EGFP tag. |