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Caspases from scleractinian coral show unique regulatory features.

Shrestha S, Tung J, Grinshpon RD, Swartz P, Hamilton PT, Dimos B, Mydlarz L, Clark AC
J Biol Chem. 2020 Oct 23;295(43):14578-14591. doi: 10.1074/jbc.RA120.014345. Epub 2020 Aug 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
166051PaCasp7aa caspase of Porites astreoides, which has higher sequence similarity with human caspase-7 but has a CARD domain and function as an initiator caspase
166052PaCasp3a caspase of Porites astreoides, which has higher sequence similarity with human caspase-3 but function similar to caspase-6
166053OfCasp3aa caspase of Orbicella faveolata, which has higher sequence similarity with human caspase-3 but has CARD domain and function as an initiator caspase
166054OfCasp3ba caspase of Orbicella faveolata, which has higher sequence similarity with human caspase-3 but function similar to caspase-6

Antibodies from Article