Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Lawrence RE, Fromm SA, Fu Y, Yokom AL, Kim DJ, Thelen AM, Young LN, Lim CY, Samelson AJ, Hurley JH, Zoncu R
Science. 2019 Nov 22;366(6468):971-977. doi: 10.1126/science.aax0364. Epub 2019 Oct 31.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
164978 | pLJM1 FLCN (WT) FLAG GFP | Lentiviral vector for FLCN expression in mammalian cells |
164979 | pLJM1 FLCN (F118D) FLAG GFP | Lentiviral vector for FLCN expression in mammalian cells |
164980 | pLJM1 FLCN (R164A) FLAG GFP | Lentiviral vector for FLCN expression in mammalian cells |
164981 | pCAG-TWIN-STREP-FLAG-FLCN | FLCN expressing vector for mammalian cells |
164982 | pCAG-GST FNIP2 | FNIP2 expressing vector for mammalian cells |
164983 | pCAG GST DEPDC5 | DEPDC5 expressing vector for mammalian cells |
164984 | pCAG-TWIN-STREP-FLAG-NPRL3 | NPRL3 expressing vector for mammalian cells |
164985 | pCAG-TWIN-STREP-FLAG-NPRL2 | NPRL2 expressing vector for mammalian cells |