NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C.
Davis OB, Shin HR, Lim CY, Wu EY, Kukurugya M, Maher CF, Perera RM, Ordonez MP, Zoncu R
Dev Cell. 2020 Dec 7. pii: S1534-5807(20)30925-4. doi: 10.1016/j.devcel.2020.11.016.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164972 | pLVX-NPC1(WT)-FLAG | Lentiviral vector for NPC1 expression in mammalian cells |
| 164973 | pLVX-NPC1(P691S)-FLAG | Lentiviral vector for NPC1 expression in mammalian cells |
| 164974 | pLVX-NPC1(F503/4A)-FLAG | Lentiviral vector for NPC1 expression in mammalian cells |
| 164975 | pLVX-NPC1(D786N)-FLAG | Lentiviral vector for NPC1 expression in mammalian cells |
| 164976 | pLVX-NPC1(P202A/F203A)-FLAG | Lentiviral vector for NPC1 expression in mammalian cells |
| 164977 | pLJM1-TMEM192-FLAG | Lentiviral vector for TMEM192 expression in mammalian cells |