Development of siRNA payloads to target KRAS-mutant cancer.
Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW
Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164926 | pInducer10b-HA-KRAS WT CO SR | Expresses HA tagged, codon Optimized and siRNA-resistant, tetracycline-inducible KRAS wild type sequence |
| 164928 | pInducer10b-HA-KRAS G12V CO SR | Expresses HA tagged, codon Optimized and siRNA-resistant, tetracycline-inducible KRASG12V sequence |