A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein.
Carver J, Dexheimer TS, Hsu D, Weng MT, Smith JL, Guha R, Jadhav A, Simeonov A, Luo J
PLoS One. 2014 Aug 5;9(8):e103836. doi: 10.1371/journal.pone.0103836. eCollection 2014.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
164925 | pInducer10b-EGFP-KRAS G12V | Expresses EGFP cDNA and KRAS G12V cDNA in mammalian cells |
164935 | pInducer10b-EGFP-KRAS-WT | Expresses EGFP cDNA and KRAS wild type cDNA in mammalian cells |