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Programmable C-to-U RNA editing using the human APOBEC3A deaminase.

Huang X, Lv J, Li Y, Mao S, Li Z, Jing Z, Sun Y, Zhang X, Shen S, Wang X, Di M, Ge J, Huang X, Zuo E, Chi T
EMBO J. 2020 Nov 16;39(22):e104741. doi: 10.15252/embj.2020104741. Epub 2020 Oct 15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
164872TC1681CURE-C2: C to U RNA Editing, with high efficiency and high off-target effects
164873TC1614CURE-X: C to U RNA Editing, with low off-target effects but also lower efficiency
164874TC1332CURE-N: C to U RNA Editing, with high efficiency and low off-target effects
164875TC1541ASplit GFP reporter expressing GFP(beta1-10) following C>U editing of the target site
164876TC1154Split GFP reporter plasmid expressing GFP (b11beta

Antibodies from Article