Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice.
Helseth AR, Hernandez-Martinez R, Hall VL, Oliver ML, Turner BD, Caffall ZF, Rittiner JE, Shipman MK, King CS, Gradinaru V, Gerfen C, Costa-Mattioli M, Calakos N
Science. 2021 Apr 23;372(6540). pii: 372/6540/eabe1931. doi: 10.1126/science.abe1931.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164819 | AAV-CAG-SPOTlight-U2GCR | Reporter to measure ISR state-dependent protein synthesis |
| 167503 | AAV-hSyn-DIO-mCReP | Conditional expression of the eIF2alpha phophatase, CReP (Ppp1r15b) |