A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).
Kaniskan HU, Szewczyk MM, Yu Z, Eram MS, Yang X, Schmidt K, Luo X, Dai M, He F, Zang I, Lin Y, Kennedy S, Li F, Dobrovetsky E, Dong A, Smil D, Min SJ, Landon M, Lin-Jones J, Huang XP, Roth BL, Schapira M, Atadja P, Barsyte-Lovejoy D, Arrowsmith CH, Brown PJ, Zhao K, Jin J, Vedadi M
Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70. doi: 10.1002/anie.201412154. Epub 2015 Feb 27.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164695 | FLAG-PRMT3 | Expression of PRMT3 with an N-terminal FLAG tag |
| 164696 | FLAG-PRMT3(E338Q) | Expression of PRMT3(E338Q) with an N-terminal FLAG tag |