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LRRK2 mediates tubulation and vesicle sorting from lysosomes.

Bonet-Ponce L, Beilina A, Williamson CD, Lindberg E, Kluss JH, Saez-Atienzar S, Landeck N, Kumaran R, Mamais A, Bleck CKE, Li Y, Cookson MR
Sci Adv. 2020 Nov 11;6(46). pii: 6/46/eabb2454. doi: 10.1126/sciadv.abb2454. Print 2020 Nov. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
164620GFP-JIP4Expresses JIP4 in mammalian cells with a GFP tag
164621mNeonGreen-JIP4Expresses JIP4 in mammalian cells with a mNeonGreen tag
1646223xflag-APEX2-LRRK2Expresses LRRK2 tagged with APEX2 and 3xFLAG
1646233xflag-APEX2-NESExpresses a nuclear exporting signal (NES) tagged with APEX2 and 3xflag
164624GFP-JIP3Expresses JIP3 with a GFP tag
164625GFP-BLOS1Expresses BLOS1 in mammalian cells with a GFP tag
164626GFP-BICD2Expresses BICD2 in mammalian cells with a GFP tag
164628GFP-STAM1Expresses STAM1 in mammalian cells with a GFP tag
164629GFP-MUTEDExpresses MUTED in mammalian cells with a GFP tag
164630GFP-RAB35Expresses RAB35 in mammalian cells with a GFP tag
1646312xmyc-RAB10Expresses RAB10 in mammalian cells with a 2xmyc tag
1646322xmyc-RAB35Expresses RAB35 in mammalian cells with a 2xmyc tag
1646332xmyc-JIP4Expresses JIP4 in mammalian cells with a 2xmyc tag

Antibodies from Article