Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration.
Yang Q, Hughes TA, Kelkar A, Yu X, Cheng K, Park S, Huang WC, Lovell JF, Neelamegham S
Elife. 2020 Oct 26;9. pii: 61552. doi: 10.7554/eLife.61552.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
164219 | ACE2 | Expresses full length human ACE2 protein, along with TagBFP reporter and Puromycin selection marker |
164220 | S1-Fc | Expresses soluble, dimeric Fc-His fusion protein for the original SARS-CoV2 Spike S1 region, along with dTomato reporter |
164221 | RBD-Fc | Expresses soluble , dimeric Fc-His fusion protein for the original SARS-CoV2 Spike RBD region, along with dTomato reporter |
164222 | ACE2-Fc | Expresses soluble , dimeric Fc-His fusion protein for the human ACE2 extracellular domain, along with dTomato reporter |