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Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.

Lee S, Ding N, Sun Y, Yuan T, Li J, Yuan Q, Liu L, Yang J, Wang Q, Kolomeisky AB, Hilton IB, Zuo E, Gao X
Sci Adv. 2020 Jul 15;6(29):eaba1773. doi: 10.1126/sciadv.aba1773. eCollection 2020 Jul. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
163636A3G-BE4.4C to T DNA base editing
163637A3G-BE5.13C to T DNA base editing
163638A3G-BE5.14C to T DNA base editing

Antibodies from Article