Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.
Lee S, Ding N, Sun Y, Yuan T, Li J, Yuan Q, Liu L, Yang J, Wang Q, Kolomeisky AB, Hilton IB, Zuo E, Gao X
Sci Adv. 2020 Jul 15;6(29):eaba1773. doi: 10.1126/sciadv.aba1773. eCollection 2020 Jul.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
163636 | A3G-BE4.4 | C to T DNA base editing |
163637 | A3G-BE5.13 | C to T DNA base editing |
163638 | A3G-BE5.14 | C to T DNA base editing |