Designed protein logic to target cells with precise combinations of surface antigens.
Lajoie MJ, Boyken SE, Salter AI, Bruffey J, Rajan A, Langan RA, Olshefsky A, Muhunthan V, Bick MJ, Gewe M, Quijano-Rubio A, Johnson J, Lenz G, Nguyen A, Pun S, Correnti CE, Riddell SR, Baker D
Science. 2020 Sep 25;369(6511):1637-1643. doi: 10.1126/science.aba6527. Epub 2020 Aug 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 163465 | HIV7-Bcl2-CD28-CD3z-T2A-EGFR | Lentiviral vector encoding a Bim-specific chimeric antigen receptor with a synthetic Bcl2 binding element |