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Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme.

Boos F, Kramer L, Groh C, Jung F, Haberkant P, Stein F, Wollweber F, Gackstatter A, Zoller E, van der Laan M, Savitski MM, Benes V, Herrmann JM
Nat Cell Biol. 2019 Apr;21(4):442-451. doi: 10.1038/s41556-019-0294-5. Epub 2019 Mar 18. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
163759pYX233-b2-DHFRGal-inducible yeast expression of the mitochondrial "clogger" protein b2(167)-DHFR
163760pYX233-b2delta-DHFRGal-inducible yeast expression of the mitochondrial "clogger" protein b2(167)delta(19)-DHFR
163761pYX233-DHFRGal-inducible yeast expression of cytosolic DHFR
163762pYX233Empty vector for Gal-inducible yeast expression
172002pNH605-PACE-YFPFluorescent reporter for Rpn4 activity
172131pNH605-HSE-YFPFluorescent reporter for Hsf1 activity
172132pNH605-CCAAT-YFPFluorescent reporter for HAP complex activity

Antibodies from Article