Non-full-length Water-Soluble CXCR4(QTY) and CCR5(QTY) Chemokine Receptors: Implication for Overlooked Truncated but Functional Membrane Receptors.
Qing R, Tao F, Chatterjee P, Yang G, Han Q, Chung H, Ni J, Suter BP, Kubicek J, Maertens B, Schubert T, Blackburn C, Zhang S
iScience. 2020 Oct 28;23(12):101670. doi: 10.1016/j.isci.2020.101670. eCollection 2020 Dec 18.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 162442 | CXCR4-SZ158a QTY | Expression in E coli and perform ligand binding in solution |
| 162443 | CXCR4-SZ146a QTY | Expression in E coli and perform ligand binding in solution |
| 162444 | CCR5-SZ218a QTY | Expression in E coli and perform ligand binding in solution |
| 162445 | CCR5-SZ190b QTY | Expression in E coli and perform ligand binding in solution |
| 162446 | CXCR4-SZ158a-sfGFP | Expression in HEK293T cell and compete ligand singaling against full-length receptors |
| 162447 | CCR5-SZ190b-sfGFP | Expression in HEK293T cell and compete ligand singaling against full-length receptors, the truncated receptor can perform signaling at high ligand concentration |