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The Cell Nucleus Serves as a Mechanotransducer of Tissue Damage-Induced Inflammation.

Enyedi B, Jelcic M, Niethammer P
Cell. 2016 May 19;165(5):1160-1170. doi: 10.1016/j.cell.2016.04.016. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
162564LR (hsp70I: cPLA2-mK2)Measuring cPLA2 activation in live cells after heat shock.
162566pSB-CMV-MCS-Puro cPLA2-mK2-P2A-EGFP-LaminB1Used for the dual color labeling of cPLA2 and LaminB1 expression.
162568pSB-CMV-MCS-Puro cPLA2-EGFPUsed as a measure of cPLA2 activation in live cells with an EGFP tag.
163844pSB-CMV-MCS-Puro dr_cPLA2-mKate2Used as a driver for the readout of cPLA2 activation in live cells with an mKate2 tag.
165400pCS2+ EGFP-3NLSExpresses nuclear localized EGFP
165401pCS2+ GCamp6-3NLSExpresses a nuclear localized genetically encoded calcium reporter.

Antibodies from Article