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An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants.

Chan KK, Tan TJC, Narayanan KK, Procko E
Sci Adv. 2021 Feb 17;7(8). pii: 7/8/eabf1738. doi: 10.1126/sciadv.abf1738. Print 2021 Feb. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
161821pcDNA3-SARS-1-RBD-8hMammalian expression plasmid for RBD of SARS-CoV-1 (Urbani strain)
161822pcDNA3-LYRa11-RBD-8hMammalian expression plasmid for RBD of bat coronavirus isolate LYRa11
161823pcDNA3-Rs7327-RBD-8hMammalian expression plasmid for RBD of bat coronavirus isolate Rs7327
161824pcDNA3-Rs4231-RBD-8hMammalian expression plasmid for RBD of bat coronavirus isolate Rs4231
161825pcDNA3-Rs4084-RBD-8hMammalian expression plasmid for RBD of bat coronavirus isolate Rs4084
161826pcDNA3-RsSHC014-RBD-8hMammalian expression plasmid for RBD of bat coronavirus isolate RsSHC014
164845pcDNA3-SARS-CoV-2-S-RBD-8his-N501YMammalian expression plasmid for RBD of SARS-CoV-2 (N501Y mutant) with 8his tag

Antibodies from Article