Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.
Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, Zhuang L, You MJ, Fang B, Li W, Metallo CM, Poyurovsky MV, Gan B
Nat Cell Biol. 2020 Apr;22(4):476-486. doi: 10.1038/s41556-020-0496-x. Epub 2020 Mar 30.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 161818 | lentiCRISPR v2-sgSLC7A11/xCT-1 | knock out SLC7A11/xCT in mammalian cells |
| 161819 | lentiCRISPR v2-sgSLC7A11/xCT-2 | knock out SLC7A11/xCT in mammalian cells |