Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity.
Zhang Y, Federation AJ, Kim S, O'Keefe JP, Lun M, Xiang D, Brown JD, Steinhauser ML
J Clin Invest. 2018 Nov 1;128(11):4898-4911. doi: 10.1172/JCI98353. Epub 2018 Oct 2.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 160941 | MSCV-HA-Nr4a1 | Generation of retrovirus for the overexpression of Nr4a1 |
| 160942 | MSCV-HA-Nr4a1-AA | Generation of retrovirus for the overexpression of Nr4a1 mutant (287C 288EAA) |
| 160943 | MSCV-HA-Nr4a1-Zf1 | Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 1 deletion) |
| 160944 | MSCV-HA-Nr4a1-Zf2 | Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 2 deletion) |
| 160945 | lentiCRISPR v2-Nr4a1sgRNA1 | Guide RNA 1 to generate Nr4a1 knockout by CRISPR |
| 160946 | lentiCRISPR v2-Nr4a1sgRNA2 | Guide RNA 2 to generate Nr4a1 knockout by CRISPR |
| 160947 | pMKO.1-shAspm | Aspm shRNA in pMKO.1 retroviral vector |
| 160948 | pMKO.1-shBub1 | Bub1 shRNA in pMKO.1 retroviral vector |
| 160949 | pMKO.1-shBirc5 | Birc5 shRNA in pMKO.1 retroviral vector |
| 160953 | pMKO.1-shCdk1 | Cdk1 shRNA in pMKO.1 retroviral vector |
| 160954 | pMKO.1-shCdc20 | Cdc20 shRNA in pMKO.1 retroviral vector |
| 160955 | pMKO.1-shCdkn3 | Cdkn3 shRNA in pMKO.1 retroviral vector |
| 160956 | pMKO.1-shCenpf | Cenpf shRNA in pMKO.1 retroviral vector |
| 160957 | pMKO.1-shEsco2 | Esco2 shRNA in pMKO.1 retroviral vector |
| 160958 | pMKO.1-shMki67 | Mki67 shRNA in pMKO.1 retroviral vector |
| 160959 | pMKO.1-shPrc1 | Prc1 shRNA in pMKO.1 retroviral vector |
| 160960 | pMKO.1-shSpc25 | Spc25 shRNA in pMKO.1 retroviral vector |
| 160961 | pMKO.1-shNuf2 | Nuf2 shRNA in pMKO.1 retroviral vector |
| 160962 | pMKO.1-shKif11 | Kif11 shRNA in pMKO.1 retroviral vector |
| 162791 | lentiCRISPR v2-Nr4a1 double gRNAs | Multiplex Guide RNAs to generate Nr4a1 knockout by CRISPR |
| 162793 | pMKO.1-shCcnb1 | Ccnb1 shRNA in pMKO.1 retroviral vector |
| 162794 | pMKO.1-shCcnb2 | Ccnb2 shRNA in pMKO.1 retroviral vector |