APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia.

Sienski G, Narayan P, Bonner JM, Kory N, Boland S, Arczewska AA, Ralvenius WT, Akay L, Lockshin E, He L, Milo B, Graziosi A, Baru V, Lewis CA, Kellis M, Sabatini DM, Tsai LH, Lindquist S
Sci Transl Med. 2021 Mar 3;13(583). pii: 13/583/eaaz4564. doi: 10.1126/scitranslmed.aaz4564. PubMed Article

Plasmids from Article

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ID	Plasmid	Purpose
160653	pGS_591	Expresses OLE1 under the control of the yeast Sup35 promoter
160652	pGS_129	Expresses Human APOE4 with a yeast secretory signal peptide under the control of a beta-estradiol inducible promoter
160651	pGS_128	Expresses Human APOE3 with a yeast secretory signal peptide under the control of a beta-estradiol inducible promoter
160650	pGS_107	Expresses Human APOE4 with a yeast secretory signal peptide under the control of the yeast Gal promoter
160541	pGS_101	Expresses Human APOE4 with a yeast secretory signal peptide under the control of the yeast Gal promoter