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Collybistin SH3-protein isoforms are expressed in the rat brain promoting gephyrin and GABA-A receptor clustering at GABAergic synapses.

George S, Bear J Jr, Taylor MJ, Kanamalla K, Fekete CD, Chiou TT, Miralles CP, Papadopoulos T, De Blas AL
J Neurochem. 2021 May;157(4):1032-1051. doi: 10.1111/jnc.15270. Epub 2021 Jan 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
160065AllCB shRNA-1 Knock Down all Collybistin isoforms
160066CBSH3+ shRNA-1 Knock Down SH3+ Collybistin isoforms
160067CBSH3+ 3m shRNA-13-point mutation negative control for CBSH3+ shRNA-1 targeting collybistin isoforms with SH3+ domain (plasmid 160066)
160068CBSH3+ shRNA-2Knock Down SH3+ Collybistin isoforms
160208CBSH3- shRNA1Knock Down MQWSH3- Collybistin isoforms
160209CBSH3- 3m shRNA1Knock Down MQWSH3- Collybistin isoforms, 3-point mutation negative control for CBSH3- shRNA1 targeting collybistin MQW-CBSH3- isoforms (Plasmid # 160208).
160210CBSH3- shRNA2Knock Down MTLSH3- Collybistin isoforms
160211CBSH3- 3m shRNA2Knock Down MTLSH3- Collybistin isoforms, 3-point mutation negative control for CBSH3- shRNA2 targeting collybistin MTL-CBSH3-isoforms (Plasmid #160210)
160212CBSH3- shRNA3Knock Down MYDSH3- Collybistin isoforms
160213CBSH3- 3m shRNA3Knock Down MYDSH3- Collybistin isoforms, 3-point mutation negative control for CBSH3- shRNA3 targeting collybistin MYD-CBSH3- isoforms (Plasmid #160212)

Antibodies from Article