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Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation.

Rahikainen R, Rijal P, Tan TK, Wu HJ, Andersson AC, Barrett JR, Bowden TA, Draper SJ, Townsend AR, Howarth M
Angew Chem Int Ed Engl. 2020 Sep 4. doi: 10.1002/anie.202009663. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
159995SpyCatcher003-mi3Expresses SpyCatcher003-mi3 in bacterial cells as virus-like particle platform for plug-and-display vaccination
159996Spy0469Expresses Streptococcus pyogenes Spy0469 (24-389) in bacterial cells
159997PsaAExpresses Streptococcus pneumoniae PsaA (19-309) in bacterial cells
159998SpyTag003-OspCExpresses Borrelia burgdorferi OspC (20-209) C129S with N-terminal SpyTag003 fusion in bacterial cells
159999SpyTag-RBDExpresses SARS-CoV-2 RBD (340-538) (receptor-binding domain from Spike) with N-terminal SpyTag fusion in mammalian cells
160000NDV-HN-SpyTagExpresses Newcastle disease virus HN protein (47-575) with C-terminal SpyTag fusion in mammalian cells

Antibodies from Article