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Reprogramming the piRNA pathway for multiplexed and transgenerational gene silencing in C. elegans.

Priyadarshini M, Ni JZ, Vargas-Velazquez AM, Gu SG, Frokjaer-Jensen C
Nat Methods. 2022 Feb;19(2):187-194. doi: 10.1038/s41592-021-01369-z. Epub 2022 Feb 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
159818pMNK54 - piRNAi 21ur-1224 - him-5piRNA-induced RNA interference (piRNAi) to induce males in transgenic animals
159819pMNK56 - piRNAi 21ur-1224 - him-8piRNA-induced RNA interference (piRNAi) to induce males in transgenic animals
159820pMNK55 - piRNAi 21ur-1224 - cku-80piRNA-induced RNA interference (piRNAi) to bias double-strand repair toward homologous recombination

Antibodies from Article