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Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.

Lawson KA, Sousa CM, Zhang X, Kim E, Akthar R, Caumanns JJ, Yao Y, Mikolajewicz N, Ross C, Brown KR, Zid AA, Fan ZP, Hui S, Krall JA, Simons DM, Slater CJ, De Jesus V, Tang L, Singh R, Goldford JE, Martin S, Huang Q, Francis EA, Habsid A, Climie R, Tieu D, Wei J, Li R, Tong AHY, Aregger M, Chan KS, Han H, Wang X, Mero P, Brumell JH, Finelli A, Ailles L, Bader G, Smolen GA, Kingsbury GA, Hart T, Kung C, Moffat J
Nature. 2020 Oct;586(7827):120-126. doi: 10.1038/s41586-020-2746-2. Epub 2020 Sep 23. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
159391Mouse Validation (mVAL) CRISPR LibraryPooled CRISPR library targets core intrinsic immune evasion genes
159392Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2Mouse lentiviral genome-wide CRISPR library
159393Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2Mouse lentiviral genome-wide CRISPR library

Antibodies from Article