mTOR generates an auto-amplification loop by triggering the betaTrCP- and CK1alpha-dependent degradation of DEPTOR.

Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, Pagano M
Mol Cell. 2011 Oct 21;44(2):317-24. doi: 10.1016/j.molcel.2011.09.005. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

Showing 1 to 3 of 3 entries

Show entries

Search table:

ID	Plasmid	Purpose
159161	pcDNA3-HA-DEPTOR S286/287/291D	Expresses DEPTOR S286/287/291D mutant in mammalian cells
159160	pcDNA3-HA-DEPTOR S286/287/291A	Expresses DEPTOR S286/287/291A mutant in mammalian cells
159159	pcDNA3-HA-DEPTOR-WT	Expresses DEPTOR in mammalian cells