Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Lin FY, Nair MS, Huang Y, Lee S, Tay NES, Rovis T, Yang HW, Xing L, Stockwell BR, Ho DD, Chavez A
J Virol. 2021 Jun 24;95(14):e0237420. doi: 10.1128/JVI.02374-20. Epub 2021 Jun 24.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 160278 | pLEX307-SARS-CoV-2-3CL | Allows for constituitive mammalian expression of the SARS-CoV-2 3CL protease via transfection or lentivirus |
| 160279 | pLEX307-SARS-CoV-2-3CL-C145A | Allows for constituitive mammalian expression of the SARS-CoV-2 3CL protease with C145A mutation via transfection or lentivirus |
| 160280 | pLEX307-SARS-CoV-3CL | Allows for constituitive mammalian expression of the SARS-CoV 3CL protease via transfection or lentivirus |
| 160281 | pLEX307-SARS-CoV-3CL-C145A | Allows for constituitive mammalian expression of the SARS-CoV 3CL protease with C145A mutation via transfection or lentivirus |
| 160283 | pLEX307-MERS-CoV-3CL-C148A | Allows for constituitive mammalian expression of the MERS-CoV 3CL protease with C145A mutation via transfection or lentivirus |
| 160284 | pLEX307-Bat-CoV-HKU9-3CL | Allows for constituitive mammalian expression of the Bat-CoV-HKU9 3CL protease via transfection or lentivirus |
| 160285 | pLEX307-Bat-CoV-HKU9-3CL-C144A | Allows for constituitive mammalian expression of the Bat-CoV-HKU9 3CL protease with C145A mutation via transfection or lentivirus |
| 160286 | pLEX307-HCoV-NL63-3CL | Allows for constituitive mammalian expression of the HCoV-NL63 3CL protease via transfection or lentivirus |
| 160287 | pLEX307-HCoV-NL63-3CL-C144A | Allows for constituitive mammalian expression of the HCoV-NL63 3CL protease with C144A mutation via transfection or lentivirus |
| 160288 | pLEX307-IBV-3CL | Allows for constituitive mammalian expression of the IBV 3CL protease via transfection or lentivirus |
| 160289 | pLEX307-IBV-3CL-C143A | Allows for constituitive mammalian expression of the IBV 3CL protease with C143A mutation via transfection or lentivirus |