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Addgene

Dual base editor catalyzes both cytosine and adenine base conversions in human cells.

Zhang X, Zhu B, Chen L, Xie L, Yu W, Wang Y, Li L, Yin S, Yang L, Hu H, Han H, Li Y, Wang L, Chen G, Ma X, Geng H, Huang W, Pang X, Yang Z, Wu Y, Siwko S, Kurita R, Nakamura Y, Yang L, Liu M, Li D
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0527-y. doi: 10.1038/s41587-020-0527-y. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
157947A&C-BEmaxMammalian expression of A&C-BEmax
157948AID-BE4max-P2A-GFPMammalian expression of AID-BE4max-P2A-GFP
157949Lenti ABE7.10-N-AIDmaxLentiviral expression of ABE7.10-N-AIDmax
157950Lenti AID-BEmaxLentiviral expression of AID-BEmax
157951Lenti U6-HBG site1-EF1alpha-UGI-P2A-GFPLentiviral expression of HBG site 1 sgRNA

Antibodies from Article