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Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain.

Zhang X, Chen L, Zhu B, Wang L, Chen C, Hong M, Huang Y, Li H, Han H, Cai B, Yu W, Yin S, Yang L, Yang Z, Liu M, Zhang Y, Mao Z, Wu Y, Liu M, Li D
Nat Cell Biol. 2020 Jun;22(6):740-750. doi: 10.1038/s41556-020-0518-8. Epub 2020 May 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
157942hyBE4maxMammalian expression of hyBE4max
157943hyA3A-BE4maxMammalian expression of hyA3A-BE4max
157944hyeA3A-BE4maxMammalian expression of hyeA3A-BE4max
157945Lenti-117G-hyA3A-BE4maxLentiviral expression of hyA3A-BE4max
157946Lenti-117G-hyeA3A-BE4maxLentiviral expression of hyeA3A-BE4max

Antibodies from Article