Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling.
Loganathan SK, Schleicher K, Malik A, Quevedo R, Langille E, Teng K, Oh RH, Rathod B, Tsai R, Samavarchi-Tehrani P, Pugh TJ, Gingras AC, Schramek D
Science. 2020 Mar 13;367(6483):1264-1269. doi: 10.1126/science.aax0902.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 158030 | pLKO-Cre stuffer v3 | lenti-viral construct with Cre recombinase and U6 driven sgRNA casette (20bp sgRNA can be cloned by digesting the stuffer 1.8kb with BsmBI). NO Cas9 |
| 158032 | pLKO-Cre stuffer v4 | lenti-viral construct with Cre recombinase and U6 driven sgRNA casette with modified tracrRNA (20bp sgRNA can be cloned by digesting the stuffer 1.8kb with BsmBI). NO Cas9 |
| 158033 | pCRISPR-Cre stuffer v4 | lenti-viral construct with Cas9, Cre recombinase and U6 driven sgRNA casette with modified tracr RNA (20bp sgRNA can be cloned by digesting the stuffer 1.8kb with BsmBI) |
| 158034 | pLKO-Cre sgAdam10 v3 | lenti-viral construct with Cre recombinase and U6 driven sgRNA against mouse Adam10 |
| 158035 | pLKO-Cre sgRipk4 v3 | lenti-viral construct with Cre recombinase and U6 driven sgRNA against mouse Ripk4 |
| 158036 | pLKO-Cre sgUroD v4 | lenti-viral construct with Cre recombinase and U6 driven sgRNA against mouse UroD |
| 158038 | pLKO-Cre sgItgb5 v3 | lenti-viral construct with Cre recombinase and U6 driven sgRNA against mouse Itgb5 |
| 158046 | pLKO-CreERT2 stuffer v3 | lenti-viral construct with tamoxifen inducible Cre recombinase and U6 driven sgRNA casette (20bp sgRNA can be cloned by digesting the stuffer 1.8kb with BsmBI). NO Cas9 |
| 158047 | pLKO-CreERT2 sgAdam10 v3 | lenti-viral construct with tamoxifen inducible Cre recombinase and U6 driven sgRNA against mouse Adam10. NO Cas9 |
| 158048 | pLKO-CreERT2 sgRipk4 v3 | lenti-viral construct with tamoxifen inducible Cre recombinase and U6 driven sgRNA against mouse Ripk4. NO Cas9 |
| 158049 | PLX306 iCre tetO NICD rtTA | lenti-viral construct with Cre recombinase and doxycycline inducible expression of mouse Notch intracellular domain |
| 158050 | PLX306 iCre tetO tomato rtTA | lenti-viral construct with Cre recombinase and doxycycline inducible expression of tdTomato |
| 158602 | pLKO-Cre sgAmotl2 v3 | lenti-viral construct with Cas9, Cre recombinbase and U6 driven sgRNA against mouse Amotl2 |