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Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3.

Phoo WW, El Sahili A, Zhang Z, Chen MW, Liew CW, Lescar J, Vasudevan SG, Luo D
Antiviral Res. 2020 Oct;182:104900. doi: 10.1016/j.antiviral.2020.104900. Epub 2020 Aug 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
155316gNS2B47NS3 L30SF31S DENV4 47 peptides from NS2B cofactor linked to NS3 full length by GGGGSGGGG linker L30SF31S mutant
155317gNS2B47NS3 S135ADENV4 47 peptides from NS2B cofactor linked to NS3 full length by GGGGSGGGG linker S135A mutant
155318eNS2B47NS3 S135ADENV4 47 peptides from NS2B cofactor linked to NS3 full length by VKTQR linker S135A mutant
155319eNS2B47NS3 L30SF31SDENV4 47 peptides from NS2B cofactor linked to NS3 full length by VKTQR linker L30SF31S mutant
155320bNS2B47NS3co-expression of DENV4 47 peptides from NS2B cofactor and NS3 full length

Antibodies from Article