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TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels.

Jia Y, Zhao Y, Kusakizako T, Wang Y, Pan C, Zhang Y, Nureki O, Hattori M, Yan Z
Neuron. 2020 Jan 22;105(2):310-321.e3. doi: 10.1016/j.neuron.2019.10.017. Epub 2019 Nov 21. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
154908GFP-CmTMC1truncatedFor the expression and purification of the truncated TMC1 protein from Chelonia mydas. The protease cleavage site was replaced with the HRV 3C site.
154909GFP-MuTMC2truncatedFor the expression and purification of the truncated TMC2 protein from Melopsittacus undulates. The protease cleavage site was replaced with the HRV 3C site.

Antibodies from Article