A myosin-7B-dependent endocytosis pathway mediates cellular entry of alpha-synuclein fibrils and polycation-bearing cargos.
Zhang Q, Xu Y, Lee J, Jarnik M, Wu X, Bonifacino JS, Shen J, Ye Y
Proc Natl Acad Sci U S A. 2020 May 19;117(20):10865-10875. doi: 10.1073/pnas.1918617117. Epub 2020 May 4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 154860 | Lenti-SLC35B2-sgRNA | Lentiviral expression of Cas9 and sgRNA targeting SLC35B2 |
| 154861 | Lenti-Myosin7B-sgRNA | Lentiviral expression of Cas9 and sgRNA targeting Myosin7B |
| 154862 | Lenti-XYLT2-sgRNA | Lentiviral expression of Cas9 and sgRNA targeting XYLT2 |
| 154863 | pLJM1-SLC35B2-FLAG | Transient or Lentiviral expression of sgRNA (Addgene#154860) resistant SLC35B2 |
| 155037 | pEGFP-C-SLC35B2 | Transient expression of EGFP-SLC35B2 |
| 155038 | pVenus-N-SLC35B2 | Transient expression of SLC35B2-Venus |