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Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates.

Rheinemann L, Downhour DM, Davenport KA, McKeown AN, Sundquist WI, Elde NC
Curr Biol. 2022 Feb 25. pii: S0960-9822(22)00240-8. doi: 10.1016/j.cub.2022.02.018. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
154248pEF1α-ancestral-retroCHMP3-HAexpresses ancestral New World monkey retroCHMP3 in mammalian cells
154249pEF1α-owl-monkey-retroCHMP3-HAexpresses owl monkey retroCHMP3 in mammalian cells
154250pEF1α-woolly-monkey-retroCHMP3(148)-HAexpresses prematurely truncated woolly monkey retroCHMP3 in mammalian cells
154251pEF1α-pygmy-marmoset-retroCHMP3(148)-HAexpresses prematurely truncated pygmy marmoset retroCHMP3 in mammalian cells
154252pEF1α-owl-monkey-retroCHMP3(148)-HAexpresses prematurely truncated owl monkey retroCHMP3 in mammalian cells
154253pEF1α -NWM-Node 1expresses reconstructed New World monkey retroCHMP3 Node 1 in mammalian cells
154254pEF1α -NWM-Node 2expresses reconstructed New World monkey retroCHMP3 Node 2 in mammalian cells
154255pEF1α -NWM-Node 3expresses reconstructed New World monkey retroCHMP3 Node 3 in mammalian cells
177922pCEP4-puroeGFPConstitutively expresses eGFP with puromycin selection

Antibodies from Article