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A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects.

Zuo E, Sun Y, Yuan T, He B, Zhou C, Ying W, Liu J, Wei W, Zeng R, Li Y, Yang H
Nat Methods. 2020 May 18. pii: 10.1038/s41592-020-0832-x. doi: 10.1038/s41592-020-0832-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
154005CMV-YE1-BE3-FNLS-CMV-mCherryExpress YE1-BE3-FNLS

Antibodies from Article