Clustering of the zeta-Chain Can Initiate T Cell Receptor Signaling.
Ma Y, Lim YJ, Benda A, Lou J, Goyette J, Gaus K
Int J Mol Sci. 2020 May 15;21(10). pii: ijms21103498. doi: 10.3390/ijms21103498.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 153543 | LIC-Z | perform light induced optogenetic clustering of TCR ζ-Chain as described in the associated publication |
| 153544 | LIC-Z-YFP | perform light induced optogenetic clustering of TCR ζ-Chain tagged with yellow fluorescent protein as described in the associated publication |
| 153545 | LIC-Z-delCry2 | this is the non-clustering version of LIC-Z tagged with mcherry |
| 153546 | LIC-Z-Y-L | this is signaling incompetent version of LIC-Z where all Tyrosine residues in ITAMs are mutated to leucine |