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Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery.

Laidou S, Alanis-Lobato G, Pribyl J, Rasko T, Tichy B, Mikulasek K, Tsagiopoulou M, Oppelt J, Kastrinaki G, Lefaki M, Singh M, Zink A, Chondrogianni N, Psomopoulos F, Prigione A, Ivics Z, Pospisilova S, Skladal P, Izsvak Z, Andrade-Navarro MA, Petrakis S
Redox Biol. 2020 Feb 11;32:101458. doi: 10.1016/j.redox.2020.101458. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
153309pT2-CMV/TetO2-EYFP-GWTet-On YFP-tagged Gateway destination vector, to be used together with pT2-TetR-neoR transposon plasmid
153310pT2-TetR-neoRTet-repressor with neomycin selection marker, to be used together with pT2-CMV/TetO2-EYFP-GW

Antibodies from Article