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Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning.

Arbab M, Shen MW, Mok B, Wilson C, Matuszek Z, Cassa CA, Liu DR
Cell. 2020 Jun 9. pii: S0092-8674(20)30632-2. doi: 10.1016/j.cell.2020.05.037. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
152989p2T-CMV-ABEmax-BlastRA-to-G base editor
152990p2T-CMV-ABEmaxCP1041-BlastRA-to-G base editor
152991p2T-CMV-BE4max-BlastRC-to-T base editor
152992p2T-CMV-EA-BE4max-NG-BlastRHigh purity C-to-T base editor
152993p2T-CMV-BE4maxCP1028-BlastRC-to-T base editor
152994p2T-CMV-AIDmax-BlastRC-to-T base editor
152995p2T-CMV-CDAmax-BlastRC-to-T base editor
152996p2T-CMV-evoAmax-BlastRC-to-T base editor
152997p2T-CMV-eA3Amax-BlastRC-to-T base editor
152998p2T-CMV-eA3A-BE5-NG-BlastRHigh purity C-to-T base editor
152999p2T-CMV-eA3AmaxNG-BlastRC-to-T base editor, NG PAM
153000p2T-CMV-eA3Amax-T31A-NG-BlastRC-to-T/G/A base editor
153001p2T-CAG-REV1-p2A-GFP-PuroROverexpression of human REV1

Antibodies from Article